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Cheapest Protease on iHerb

Ranked by real cost per 10,000 USP of Protease — cheapest value first.

Prices updated Jul 25, 2026 · 25 products · Prices in USD

The priciest option here costs about 11.0× more per 10,000 USP of Protease than the best-value pick Swanson. For the same daily dose, choosing by cost per unit instead of sticker price can meaningfully cut your yearly spend.
#ProductDoseServingsPrice (USD)Cost per 10,000 USP
1
Swanson, Pancreatin 4X, 375 mg, 300 Enteric-Coated Tablets
Swanson, Pancreatin 4X, 375 mg, 300 Enteric-Coated Tablets
Swanson
75,000 USP15027.190.024View on iHerb →
2
Source Naturals, Pancreatin 8X, 100 Capsules
Source Naturals, Pancreatin 8X, 100 Capsules
Source Naturals
200,000 USP5025.840.026View on iHerb →
3
Vital Nutrients, Pancreatic Enzymes , 180 Capsules
Vital Nutrients, Pancreatic Enzymes , 180 Capsules
Vital Nutrients
223,000 USP9075.990.038View on iHerb →
4
Vital Nutrients, Pancreatic Enzymes, 90 Capsules
Vital Nutrients, Pancreatic Enzymes, 90 Capsules
Vital Nutrients
223,000 USP4539.990.040View on iHerb →
5
Nutricost, Lactase Enzyme Complex, 3,000 ALU, 120 Capsules
Nutricost, Lactase Enzyme Complex, 3,000 ALU, 120 Capsules
Nutricost
30,000 HUT12014.950.042View on iHerb →
6
Metagenics, SpectraZyme® Pancreatic Enzymes, 90 Tablets
Metagenics, SpectraZyme® Pancreatic Enzymes, 90 Tablets
Metagenics
135,000 USP9061.950.051View on iHerb →
7
Nutricost, Digestive Enzymes, 620 mg, 120 Capsules
Nutricost, Digestive Enzymes, 620 mg, 120 Capsules
Nutricost
30,000 HUT12019.990.056View on iHerb →
8
Pure Synergy, Enzyme Power™, 90 Capsules
Pure Synergy, Enzyme Power™, 90 Capsules
Pure Synergy
100,000 HUT9052.740.059View on iHerb →
9
BIOptimizers, Masszymes, 90 Veggie Caps
BIOptimizers, Masszymes, 90 Veggie Caps
BIOptimizers
143,000 HUT3026.990.063View on iHerb →
10
Carlson, Natural Digestive Enzymes with Protease, Amylase & Lipase, 250 Tablets
Carlson, Natural Digestive Enzymes with Protease, Amylase & Lipase, 250 Tablets
Carlson
30,000 USP25057.380.077View on iHerb →
11
Carlson, Natural Digestive Enzymes, 100 Tablets
Carlson, Natural Digestive Enzymes, 100 Tablets
Carlson
30,000 USP10025.420.085View on iHerb →
12
MRM Nutrition, Digest-All®, 30 Capsules
MRM Nutrition, Digest-All®, 30 Capsules
MRM Nutrition
50,000 HUT156.490.087View on iHerb →
13
Carlson, Natural Digestive Enzymes , 50 Tablets
Carlson, Natural Digestive Enzymes , 50 Tablets
Carlson
30,000 USP5014.370.096View on iHerb →
14
MRM Nutrition, Gluten Aid, 60 Vegetarian Capsules
MRM Nutrition, Gluten Aid, 60 Vegetarian Capsules
MRM Nutrition
33,000 HUT6019.990.101View on iHerb →
15
Vital Nutrients, Pancreatin & Ox Bile Extract, 60 Capsules
Vital Nutrients, Pancreatin & Ox Bile Extract, 60 Capsules
Vital Nutrients
111,400 USP3033.990.102View on iHerb →
16
Terry Naturally, Clinical Digestive Enzymes , 90 Tablets
Terry Naturally, Clinical Digestive Enzymes , 90 Tablets
Terry Naturally
54,000 USP4524.760.102View on iHerb →
17
Pure Encapsulations, Digestive Enzymes Ultra with Betaine HCl, 180 Capsules
Pure Encapsulations, Digestive Enzymes Ultra with Betaine HCl, 180 Capsules
Pure Encapsulations
60,000 HUT9071.500.132View on iHerb →
18
Pure Encapsulations, Digestive Enzymes Ultra, 90 Capsules
Pure Encapsulations, Digestive Enzymes Ultra, 90 Capsules
Pure Encapsulations
60,000 HUT4538.000.141View on iHerb →
19
Pure Encapsulations, Digestive Enzymes Ultra With Betaine HCl, 90 Capsules
Pure Encapsulations, Digestive Enzymes Ultra With Betaine HCl, 90 Capsules
Pure Encapsulations
60,000 HUT4538.500.143View on iHerb →
20
Houston Enzymes, AFP Peptizyde, 90 Capsules
Houston Enzymes, AFP Peptizyde, 90 Capsules
Houston Enzymes
31,875 HUT9041.990.146View on iHerb →
21
Healths Harmony, Candida Complex, 120 Capsules
Healths Harmony, Candida Complex, 120 Capsules
Healths Harmony
25,000 HUT6021.970.147View on iHerb →
22
Houston Enzymes, TriEnza, Enzyme For Digestive Intolerances, 60 Capsules
Houston Enzymes, TriEnza, Enzyme For Digestive Intolerances, 60 Capsules
Houston Enzymes
65,000 HUT3028.990.149View on iHerb →
23
Dr. Mercola, Serrapeptase Enzymes , 60 Capsules
Dr. Mercola, Serrapeptase Enzymes , 60 Capsules
Dr. Mercola
40,000 SPU6043.990.183View on iHerb →
24
BodyHealth, Digestive Enzymes With Betaine, Pancreatin & Pepsin, 180 Capsules
BodyHealth, Digestive Enzymes With Betaine, Pancreatin & Pepsin, 180 Capsules
BodyHealth
20,000 USP9038.950.216View on iHerb →
25
Bariatric Fusion, Digestive Support , 60 Capsules
Bariatric Fusion, Digestive Support , 60 Capsules
Bariatric Fusion
21,000 HUT6027.990.222View on iHerb →

How we rank Protease

Two supplements can list the same dose per serving yet cost very differently once you account for how many servings are in the bottle. We calculate the total nutrient in each container (dose per serving × servings per container), divide the current price by that total, and rank by the resulting cost per unit. Lower is better. Because prices are refreshed automatically, this ranking reflects today's iHerb pricing rather than a snapshot from months ago.

Cost per unit is a starting point, not the whole story — the ideal form, third-party testing, and other ingredients matter too. Always check the label and consult a healthcare professional before starting a supplement.

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Prices update automatically and may differ from iHerb at checkout. Rankings are based on cost per unit of the listed nutrient and are for informational purposes only — not medical advice. Links to iHerb are affiliate links.