Cheapest OptiMSM on iHerb

Ranked by real cost per 100 mg of OptiMSM — cheapest value first.

Prices updated Jul 25, 2026 · 21 products · Prices in USD

The priciest option here costs about 2,138.4× more per 100 mg of OptiMSM than the best-value pick Dr. Mercola. For the same daily dose, choosing by cost per unit instead of sticker price can meaningfully cut your yearly spend.
#ProductDoseServingsPrice (USD)Cost per 100 mg
1
Dr. Mercola, MSM, Methylsulfonylmethane Sulfur Complex, 60 Capsules
Dr. Mercola, MSM, Methylsulfonylmethane Sulfur Complex, 60 Capsules
Dr. Mercola
1,000 mg3018.700.062View on iHerb →
2
The Vitamin Shoppe, Glucosamine Chondroitin MSM, 360 Capsules
The Vitamin Shoppe, Glucosamine Chondroitin MSM, 360 Capsules
The Vitamin Shoppe
500 mg18059.990.067View on iHerb →
3
The Vitamin Shoppe, Glucosamine Chondroitin MSM, 240 Capsules
The Vitamin Shoppe, Glucosamine Chondroitin MSM, 240 Capsules
The Vitamin Shoppe
500 mg12044.990.075View on iHerb →
4
Natural Factors, OsteoMove, Joint Care, 120 Tablets
Natural Factors, OsteoMove, Joint Care, 120 Tablets
Natural Factors
600 mg6031.470.087View on iHerb →
5
Paradise Herbs, Whole-Woman® Collagen, 120 Vegetarian Capsules
Paradise Herbs, Whole-Woman® Collagen, 120 Vegetarian Capsules
Paradise Herbs
400 mg6026.240.109View on iHerb →
6
Paradise Herbs, Whole-Woman® Collagen, 60 Vegetarian Capsules
Paradise Herbs, Whole-Woman® Collagen, 60 Vegetarian Capsules
Paradise Herbs
400 mg3014.990.125View on iHerb →
7
Emerald Laboratories, Collagen Health for Men & Women, 90 Vegetable Caps
Emerald Laboratories, Collagen Health for Men & Women, 90 Vegetable Caps
Emerald Laboratories
750 mg3030.560.136View on iHerb →
8
ALLMAX, ALLFLEX®, All-In-One Joint Formula, 60 Capsules
ALLMAX, ALLFLEX®, All-In-One Joint Formula, 60 Capsules
ALLMAX
450 mg3020.330.151View on iHerb →
9
The Vitamin Shoppe, Triple Strength Glucosamine Chondroitin With MSM, 120 Tablets
The Vitamin Shoppe, Triple Strength Glucosamine Chondroitin With MSM, 120 Tablets
The Vitamin Shoppe
500 mg6047.990.160View on iHerb →
10
Ghost, Joint, Kiwi Strawberry, 7.9 oz (225 g)
Ghost, Joint, Kiwi Strawberry, 7.9 oz (225 g)
Ghost
1,000 mg3049.990.167View on iHerb →
11
Ghost, Joint, Orange Cream, 8.5 oz (240 g)
Ghost, Joint, Orange Cream, 8.5 oz (240 g)
Ghost
1,000 mg3049.990.167View on iHerb →
12
The Vitamin Shoppe, Triple Strength Glucosamine Chondroitin With MSM, 60 Tablets
The Vitamin Shoppe, Triple Strength Glucosamine Chondroitin With MSM, 60 Tablets
The Vitamin Shoppe
500 mg3026.990.180View on iHerb →
13
Emerald Laboratories, Joint Health, 90 Vegetable Caps
Emerald Laboratories, Joint Health, 90 Vegetable Caps
Emerald Laboratories
500 mg3040.460.270View on iHerb →
14
Emerald Laboratories, Levagen+® Pea+ with Enhanced LipiSperse®, 60 Vegetable Capsules
Emerald Laboratories, Levagen+® Pea+ with Enhanced LipiSperse®, 60 Vegetable Capsules
Emerald Laboratories
500 mg3044.060.294View on iHerb →
15
The Vitamin Shoppe, Ultimate Gold Joint Care, 60 Tablets
The Vitamin Shoppe, Ultimate Gold Joint Care, 60 Tablets
The Vitamin Shoppe
250 mg3024.990.333View on iHerb →
16
Emerald Laboratories, Osteo Bone Health, 180 Vegetable Caps
Emerald Laboratories, Osteo Bone Health, 180 Vegetable Caps
Emerald Laboratories
250 mg3044.960.600View on iHerb →
17
Emerald Laboratories, Osteo Bone Health, 90 Vegetable Caps
Emerald Laboratories, Osteo Bone Health, 90 Vegetable Caps
Emerald Laboratories
250 mg1524.260.647View on iHerb →
18
Emerald Laboratories, Meriva Turmeric +, 60 Vegetable Caps
Emerald Laboratories, Meriva Turmeric +, 60 Vegetable Caps
Emerald Laboratories
125 mg3032.360.863View on iHerb →
19
Emerald Laboratories, Women's 45+, Clinical + Multi, 120 Vegetable Caps
Emerald Laboratories, Women's 45+, Clinical + Multi, 120 Vegetable Caps
Emerald Laboratories
100 mg3054.861.83View on iHerb →
20
Maxi Health, Maxi Longevity™, Multi For Women Over 50, 60 Maxicaps
Maxi Health, Maxi Longevity™, Multi For Women Over 50, 60 Maxicaps
Maxi Health
50 mg3029.992.00View on iHerb →
21
Purity Products, JointGel, Mixed-Berry, 8.99 oz (255 g)
Purity Products, JointGel, Mixed-Berry, 8.99 oz (255 g)
Purity Products
2 g3059.95133.22View on iHerb →

How we rank OptiMSM

Two supplements can list the same dose per serving yet cost very differently once you account for how many servings are in the bottle. We calculate the total nutrient in each container (dose per serving × servings per container), divide the current price by that total, and rank by the resulting cost per unit. Lower is better. Because prices are refreshed automatically, this ranking reflects today's iHerb pricing rather than a snapshot from months ago.

Cost per unit is a starting point, not the whole story — the ideal form, third-party testing, and other ingredients matter too. Always check the label and consult a healthcare professional before starting a supplement.

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Prices update automatically and may differ from iHerb at checkout. Rankings are based on cost per unit of the listed nutrient and are for informational purposes only — not medical advice. Links to iHerb are affiliate links.